The Upington Business Chamber is a local organisation of businesses and companies in Upington with the intention to develop and further the interests of local businesses.

Many businesses are international operating companies with offices in South Africa.

Members of the Chamber of Commerce includes international and local operating companies, such as lawyers, property developers, tourism companies, airlines, manufacturing companies, import and export businesses, banks, finance companies, attorneys, employment agencies, IT and electronics manufacturers etc.

The Upington Business Chamber's main activities are, among others, safeguarding and representing the interest of business and sharing business experiences on both government and civil society platforms. The chamber also organises business events that provides its members with marketing and training opportunities.

The main industries in the area are: agriculture Renewable energy,and tourism.