The Mafikeng Campus is located in the capital of the North West Province and boast an international ambience on Campus, with students from 22 different countries.  The Campus has a rural atmosphere, with solid buildings and a safe environment with 24 hour Protection Services.   A range of undergraduate and post-graduate programmes in five faculties are offered on full-time bases. Master's degrees are offered by dissertation or by taught courses and a mini dissertation, while Doctoral degrees are offered by dissertation.

Unique characteristics of  Mafikeng Campus is a career-oriented training in English; it is  modern campus situated in the capital of North-West Province; there is excellent
sporting facilities with an active cultural and healthy residence life; excellent student support services, such as a counseling centre, health services and assistance for disabled persons; and technologically well equipped facilities, among which a library with study rooms that are open 24 hours a day.  It is the second largest of the NWU’s three campuses with 9 453 students enrolled for 2014.